The values for the hydrolysis of creatine phosphate (creatine-P) and glucose-6-phosphate (G-6-P) are — Thermodynamics and Thermochemistry Chemistry Question
Question
The $\Delta G^\circ$ values for the hydrolysis of creatine phosphate (creatine-P) and glucose-6-phosphate (G-6-P) are<br>(i) $\text{Creatine-P} + \text{H}_2\text{O} \to \text{Creatine} + \text{P}; \Delta G^\circ = -29.2\text{ kJ}$<br>(ii) $\text{G-6-P} + \text{H}_2\text{O} \to \text{G} + \text{P}; \Delta G^\circ = -12.4\text{ kJ}$<br>$\Delta G^\circ$ for the reaction: $\text{G-6-P} + \text{Creatine} \to \text{G} + \text{Creatine-P}$, is
💡 Solution & Explanation
Target reaction requires adding Eq(ii) to the reverse of Eq(i). $\Delta G^\circ = \Delta G^\circ_{\text{ii}} - \Delta G^\circ_{\text{i}} = -12.4 - (-29.2) = +16.8\text{ kJ}$.