Simple ketones resist forming open-chain ketals due to steric hindrance. However, they readily react — Aldehydes Ketones and Carboxylic Acids Chemistry Question
Question
Simple ketones resist forming open-chain ketals due to steric hindrance. However, they readily react with which of the following compounds to form highly stable cyclic ketals?
Answer: B
💡 Solution & Explanation
Ketones react efficiently with Ethylene glycol (a 1,2-diol) under mildly acidic conditions to form stable 5-membered cyclic ketals. The formation is driven forward by entropy and continuous water removal.
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