What is the correct IUPAC sequential numbering path for a substituent-bearing bicyclo compound? — IUPAC and Nomenclature Chemistry Question

💡 Solution & Explanation

The framework numbering of a bicyclo system is rigid: it must start at a bridgehead and follow the decreasing bridge lengths (longest $\rightarrow$ medium $\rightarrow$ shortest), using lowest locants only as a tie-breaker.