When translating a 3D structure into a 2D Fischer Projection, vertical lines represent bonds project β Isomerism and Stereochemistry Chemistry Question
Question
When translating a 3D structure into a 2D Fischer Projection, vertical lines represent bonds projecting away from the viewer. If the lowest priority group (Group 4) lands on the vertical line, how is the absolute configuration assigned?
π‘ Solution & Explanation
In the specialized geometry of a Fischer projection, vertical lines strictly represent bonds plunging backward into the page (identical to a dashed wedge). Because Group 4 is situated on a vertical line, it is in the ideal position. Thus, the $1 \rightarrow 2 \rightarrow 3$ trace is completely valid, and a clockwise path yields an 'R' configuration without any necessary reversal.