In the classical geometrical isomerism nomenclature of aldoximes (), how is the 'Syn' stereochemical — Isomerism and Stereochemistry Chemistry Question
Question
In the classical geometrical isomerism nomenclature of aldoximes ($R-CH=N-OH$), how is the 'Syn' stereochemical configuration strictly defined?
Answer: C
💡 Solution & Explanation
The specialized 'Syn' and 'Anti' descriptors are utilized for systems containing stereogenic nitrogen atoms. For aldoximes, the reference points are the Hydrogen on the carbon and the $-OH$ on the nitrogen. If the $-H$ and $-OH$ groups are spatially located on the *same side* of the restricted $C=N$ bond, the isomer is explicitly designated as 'Syn'.
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