To synthesize monodeuterobenzene () specifically without side products, which of the following react β Hydrocarbons Chemistry Question
Question
To synthesize monodeuterobenzene ($C_6H_5D$) specifically without side products, which of the following reaction sequences is optimal?
Answer: A
π‘ Solution & Explanation
Aromatic Grignard reagents ($PhMgBr$) are powerful bases. When quenched with heavy water ($D_2O$), the phenyl carbanion cleanly abstracts a deuteron ($D^+$) to yield $C_6H_5D$ and $Mg(OD)Br$.
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