In the molecule 1-fluorobutane (), after which carbon atom does the effect of the fluorine atom beco β GOC and Organic Chemistry Basics Chemistry Question
Question
In the molecule 1-fluorobutane ($F-CH_2-CH_2-CH_2-CH_3$), after which carbon atom does the $-I$ effect of the fluorine atom become practically negligible?
Answer: C
π‘ Solution & Explanation
The inductive effect is a permanent polarization of $\sigma$ -bonds that attenuates rapidly with distance. It is strongest at the $\alpha$ -carbon, weaker at the $\beta$ -carbon, and is generally considered negligible beyond the third carbon atom (C3).
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