The overall 3D folding of an entire single polypeptide chain into a functional globular shape repres — Biomolecules Chemistry Question
Question
The overall 3D folding of an entire single polypeptide chain into a functional globular shape represents its tertiary structure. Which of the following forces does NOT stabilize tertiary structure?
Answer: C
💡 Solution & Explanation
Tertiary protein structure is rigorously stabilized by hydrogen bonds, covalent disulfide ($-S-S-$) bridges, ionic bonds, and hydrophobic forces. Phosphodiester bonds exist only in the backbone of nucleic acids (DNA/RNA).
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