The tertiary structure of a standard globular protein dictates its exact 3D functional topography. W — Biomolecules Chemistry Question
Question
The tertiary structure of a standard globular protein dictates its exact 3D functional topography. Which of the following specific intermolecular/intramolecular forces absolutely does NOT actively contribute to stabilizing this complex tertiary folding?
Answer: B
💡 Solution & Explanation
Tertiary protein structure is rigorously stabilized by hydrogen bonds, covalent disulfide ($-S-S-$) bridges between closely aligned cysteines, ionic salt bridges, and hydrophobic forces. Phosphodiester bonds are completely unrelated to proteins; they form the rigid backbone strictly in nucleic acids (DNA/RNA).
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