Which of the following naturally occurring -amino acids uniquely incorporates a secondary amine group directly into its core cyclic structure, significantly increasing structural rigidity and classify

Question

Which of the following naturally occurring $\alpha$ -amino acids uniquely incorporates a secondary amine group directly into its core cyclic structure, significantly increasing structural rigidity and classifying it chemically as an imino acid?

Prashant Kotian · Accepted Answer

Correct answer: C. Proline features an aliphatic side chain that covalently connects back to the -amino nitrogen, forming a rigid five-membered pyrrolidine ring. Because this nitrogen is securely bonded to two distinct carbon atoms, it constitutes a secondary amine, forcing sharp kinks in protein -helices.

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