Contrast the reduction of propanamide with against treating it with Bromine and aqueous . What are t — Amines Chemistry Question
Question
Contrast the reduction of propanamide with $LiAlH_4$ against treating it with Bromine and aqueous $NaOH$. What are the respective primary amine products?
Answer: A
💡 Solution & Explanation
$LiAlH_4$ directly converts the $-C=O$ group to $-CH_2-$, retaining all carbons (yields Propan-1-amine). $Br_2/NaOH$ is the Hofmann bromamide degradation, which excises the carbonyl carbon as carbonate, stepping down the chain (yields Ethanamine).
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