The direct reductive amination of an aldehyde or ketone with a primary amine proceeds via the format β Amines Chemistry Question
Question
The direct reductive amination of an aldehyde or ketone with a primary amine proceeds via the formation of an unstable intermediate. What is this intermediate called?
Answer: C
π‘ Solution & Explanation
The amine nucleophilically attacks the carbonyl carbon, initiating a condensation that expels a molecule of water to form an unstable intermediate featuring a carbon-nitrogen double bond ($>C=N-$), known strictly as an imine or Schiff's base.
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