In the Hofmann ammonolysis reaction sequence, if a very large excess of the alkyl halide () is reacted with ammonia, what is the final major organic product isolated?

Question

In the Hofmann ammonolysis reaction sequence, if a very large excess of the alkyl halide ($R-X$) is reacted with ammonia, what is the final major organic product isolated?

Prashant Kotian · Accepted Answer

Correct answer: D. Providing a vast excess of the alkyl halide ensures that the nucleophilic nitrogen center continues to react until every single available site is fully alkylated, driving the reaction to the terminal quaternary ammonium salt ().

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