To synthesize pure p-bromoaniline from aniline, the amine group must be temporarily "protected" to h — Amines Chemistry Question
Question
To synthesize pure p-bromoaniline from aniline, the amine group must be temporarily "protected" to hinder polysubstitution. What chemical reagent is utilized for this protection step?
Answer: B
💡 Solution & Explanation
Aniline is reacted with acetic anhydride to form acetanilide. The bulky acetyl group physically hinders ortho attack, and the highly electronegative carbonyl withdraws electron density via resonance, heavily reducing ring activation for controlled para-substitution.
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