In the identical Hofmann ammonolysis reaction sequence, if a very large excess of the alkyl halide ( — Amines Chemistry Question
Question
In the identical Hofmann ammonolysis reaction sequence, if a very large excess of the alkyl halide ($R-X$) is intentionally reacted with a limited amount of ammonia, what is the final major organic product isolated?
Answer: D
💡 Solution & Explanation
The $S_N2$ reaction cascades through all substitution stages. Providing a vast excess of the alkyl halide ensures that the nucleophilic nitrogen center continues to react until every single available site is fully alkylated, completely driving the reaction to the terminal quaternary ammonium salt ($R_4N^+ X^-$).
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