Intramolecular aldol condensation of a dicarbonyl compound strictly prefers to form which size of cy β Aldehydes Ketones and Carboxylic Acids Chemistry Question
Question
Intramolecular aldol condensation of a dicarbonyl compound strictly prefers to form which size of cyclic rings due to thermodynamic considerations?
Answer: B
π‘ Solution & Explanation
Intramolecular aldol reactions are driven by the stability of the resulting products. 5- and 6-membered rings are heavily favored due to minimized angle strain and torsional strain.
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