According to Popoff's rule for the vigorous oxidative cleavage of unsymmetrical ketones (using or acidic ), how does the carbon chain preferentially fragment?

Question

According to Popoff's rule for the vigorous oxidative cleavage of unsymmetrical ketones (using $HNO_3$ or acidic $KMnO_4$), how does the carbon chain preferentially fragment?

Prashant Kotian · Accepted Answer

Correct answer: B. Popoff's rule dictates that during oxidative cleavage of mixed ketones, the highly oxidized group preferentially remains attached to the smaller alkyl chain, forming a specific mixture of acids.

💡 Solution & Explanation

Practice 22,000+ questions like this