Alcohols Phenols and EthershardMCQ SINGLE⭐ Must-Do

Can phenols be utilized directly as substrates in the Williamson ether synthesis, and if so, what isAlcohols Phenols and Ethers Chemistry Question

Question

Can phenols be utilized directly as substrates in the Williamson ether synthesis, and if so, what is their specific role?

Answer: B

💡 Solution & Explanation

Phenols cannot act as the substrate (alkyl halide equivalent) because the $C-O$ bond has partial double bond character. However, when treated with a base ($NaOH$), phenol forms the nucleophilic phenoxide ion, which can attack a primary alkyl halide to form an alkyl aryl ether.

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