The decreasing order of reactivity of (i) (ii) (iii) (iv) ()2O Towards nucleophilic acyl substitution is

Question

The decreasing order of reactivity of (i) $CH_3COCl$ (ii) $CH_3COOC_2H_5$ (iii) $CH_3CONH_2$ (iv) ($CH_3CO$)2O Towards nucleophilic acyl substitution is

Prashant Kotian · Accepted Answer

Correct answer: B. In derivatives of carboxylic acids the reactivity depends on the basic character of the leaving group. As the basic character increases, reactivity decreases. The order of basic character of the leaving group is: 3 3 2 Cl CH COO CH CO NH So, the reactivity order will b 3 2 3 3 2 5 3 2 CH CONH CH CO O CH COOC H CH COCl

💡 Solution & Explanation

Practice 22,000+ questions like this