Which of the following statements accurately describe leaving group ability (nucleofugality)? — Reaction Mechanism Chemistry Question
Question
Which of the following statements accurately describe leaving group ability (nucleofugality)?
Answer: A,B,D
💡 Solution & Explanation
Leaving groups depart with an electron pair. The more stable the resulting anion, the better the leaving group. Weak bases are stable anions. $I^-$ is a very weak base (conjugate of strong acid $HI$) making it an excellent leaving group. Strongly basic ions like $OH^-$ and $RO^-$ are very poor leaving groups unless protonated first.
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