Under the strict application of Cahn-Ingold-Prelog (CIP) sequence rules for determining R/S absolute — Isomerism and Stereochemistry Chemistry Question
Question
Under the strict application of Cahn-Ingold-Prelog (CIP) sequence rules for determining R/S absolute configuration, which of the following represents the correct descending priority order for the given groups?
Answer: C
💡 Solution & Explanation
Priority is determined by the atomic number of the directly attached atom. In option C, Oxygen (8) > Nitrogen (7) > Carbon (6) > Hydrogen (1), which accurately reflects the correct descending CIP priority. In B, $-Ph$ has a Carbon attached to C,C,C, while $-CHO$ has a Carbon attached to O,O,H. $-CHO$ > $-Ph$, so B is incorrect.
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