In the classical geometrical isomerism nomenclature of oximes, the stereochemical descriptors 'Syn' — Isomerism and Stereochemistry Chemistry Question
Question
In the classical geometrical isomerism nomenclature of oximes, the stereochemical descriptors 'Syn' and 'Anti' are utilized. For an unsymmetrical ketoxime, how is this nomenclature properly and formally assigned?
Answer: B
💡 Solution & Explanation
For unsymmetrical ketoximes ($R-C(R')=N-OH$), where two different alkyl groups are attached to the central carbon, the IUPAC convention assigns 'syn' and 'anti' relative to the alphabetically preferred alkyl group. If the $-OH$ group is on the same side as the alphabetically prior group, it is named 'syn'.
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