In the Baeyer-Villiger oxidation of an unsymmetrical ketone to an ester, the regioselectivity is det — Reaction Mechanism Chemistry Question

💡 Solution & Explanation

In the Baeyer-Villiger oxidation, the group that migrates is the one better able to stabilize a partial positive charge during the transition state. The established migratory aptitude order is: Tertiary Alkyl > Secondary Alkyl > Primary Alkyl > Methyl. Hydrogen migrates very readily (making aldehydes yield carboxylic acids). Therefore, A, C, and D are correct, while B is false.