GOC and Organic Chemistry BasicshardMCQ MULTIPLE

Which of the following organic compounds exhibit sufficient acidic character to react completely witGOC and Organic Chemistry Basics Chemistry Question

Question

Which of the following organic compounds exhibit sufficient acidic character to react completely with sodium amide ($NaNH_2$), evolving ammonia gas ($NH_3$) as a byproduct?

Answer: A,B,C,D

💡 Solution & Explanation

Sodium amide ($NaNH_2$) contains the extremely strong base, the amide ion ($NH_2^-$). It can abstract protons from any compound more acidic than ammonia ($NH_3$, $pKa \approx 38$). This includes terminal alkynes ($pKa \approx 25$), alcohols ($pKa \approx 16$), phenols ($pKa \approx 10$), and carboxylic acids ($pKa \approx 5$). Thus, all the given compounds will react.

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