Evaluate the following list of common substituent groups: , , , , , , , . How many of these explicitly listed groups exert a negative inductive () effect and generally increase the acidic strength of

Question

Evaluate the following list of common substituent groups: $-NO_2$, $-CN$, $-F$, $-COOH$, $-Cl$, $-CH_3$, $-C_2H_5$, $-O^-$. How many of these explicitly listed groups exert a negative inductive ($-I$) effect and generally increase the acidic strength of carboxylic acids?

Prashant Kotian · Accepted Answer

Correct answer: 5. The groups that exert an electron-withdrawing () effect are , , , , and (Total 5). The alkyl groups (, ) and the anionic oxygen () exert a effect.

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