BiomoleculesmediumNUMERICAL

How many moles of acetic anhydride are stoichiometrically required to completely acetylate one mole Biomolecules Chemistry Question

Question

How many moles of acetic anhydride are stoichiometrically required to completely acetylate one mole of cyclic $\alpha$ -D-glucopyranose?

Answer: 5

💡 Solution & Explanation

Cyclic $\alpha$ -D-glucopyranose features five free hydroxyl (-OH) groups per molecule (one at the anomeric hemiacetal carbon, and four standard alcoholic groups at C2, C3, C4, C6). Each hydroxyl reacts with one equivalent of acetic anhydride, consuming 5 moles in total to form glucose pentaacetate.

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