When dealing with polysubstituted benzenes, which of the following rules accurately describe the dir — Aromatic Hydrocarbons Chemistry Question

💡 Solution & Explanation

In polysubstituted benzenes, strongly activating groups (like $-OH, -NH_2$) take precedence over weak activators or deactivators in dictating orientation. When directing effects reinforce each other, the major product matches this combined preference. Steric hindrance strongly disfavors the entry of a third group between two meta substituents.