The carbylamine reaction is a characteristic chemical test strictly identifying primary amines. Which highly reactive, electron-deficient electrophilic intermediate is generated exclusively during thi

Question

The carbylamine reaction is a characteristic chemical test strictly identifying primary amines. Which highly reactive, electron-deficient electrophilic intermediate is generated exclusively during this reaction sequence to attack the amine nitrogen?

Prashant Kotian · Accepted Answer

Correct answer: B. In the carbylamine test, chloroform () reacts with a strong base (). The base removes the acidic proton to form a trichloromethyl carbanion, which subsequently undergoes -elimination of a chloride ion () to generate the highly reactive, neutral electrophile dichlorocarbene (). The primary amine nucleophilically attacks this carbene.

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