How many moles of acetic anhydride are stoichiometrically required to completely acetylate one mole — Biomolecules Chemistry Question
Question
How many moles of acetic anhydride are stoichiometrically required to completely acetylate one mole of cyclic $\alpha$ -D-glucopyranose?
Answer: 5
💡 Solution & Explanation
Cyclic $\alpha$ -D-glucopyranose features five free hydroxyl (-OH) groups per molecule (one at the anomeric hemiacetal carbon, and four standard alcoholic groups at C2, C3, C4, C6). Each hydroxyl reacts with one equivalent of acetic anhydride, consuming 5 moles in total to form glucose pentaacetate.
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