Reaction MechanismhardMCQ MULTIPLE

For the nucleophilic acyl substitution () mechanism characteristic of carboxylic acid derivatives, wReaction Mechanism Chemistry Question

Question

For the nucleophilic acyl substitution ($AN+DN$) mechanism characteristic of carboxylic acid derivatives, which of the following statements is/are correct?

Answer: A,B,D

💡 Solution & Explanation

The $AN+DN$ mechanism explicitly occurs in two discrete steps: addition of the nucleophile to form a tetrahedral intermediate (A is true), followed by elimination of the leaving group to reform the planar carbonyl (B is true). It is strictly not a concerted process (C is false). Electron-withdrawing groups make the carbonyl carbon more positive, lowering the activation energy for the initial nucleophilic attack (D is true).

💬
Still have doubts about this question?
Send it to our AI chemistry tutor on WhatsApp — gets answered in minutes
Ask on WhatsApp →

Practice 22,000+ questions like this

AI-adaptive practice, video lectures, and full JEE Advanced Chemistry content — all in one place.

JEE Advanced · JEE Mains · NEET · IChO · AP Chemistry