When utilizing the universally accepted Cahn-Ingold-Prelog (CIP) sequence rules, which of the following specific principles are actively applied to assign substituent priorities?

Question

Prashant Kotian · Accepted Answer

Correct answer: A,B,D. The CIP rules strictly rely on atomic number, not steric bulk or mass (unless distinguishing isotopes, where higher mass wins, e.g., D > H). Multiple bonds are treated as multiple single bonds to that specific element type. The sequence dictates walking outward atom-by-atom until the very first point of atomic difference is established.

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