BiomoleculeshardMCQ SINGLE

In the continuous polymeric backbone of naturally occurring nucleic acids, sequential nucleotide monBiomolecules Chemistry Question

Question

In the continuous polymeric backbone of naturally occurring nucleic acids, sequential nucleotide monomers are covalently tethered to one another via which specific molecular linkage?

Answer: B

💡 Solution & Explanation

Polynucleotide chains (like DNA and RNA) are strictly synthesized by joining nucleotides together via phosphodiester linkages. These specific ester bonds form between the $3'$ hydroxyl group of the pentose sugar of one nucleotide and the $5'$ phosphate group of the adjacent nucleotide.

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