Glucose reacts with anhydrous methyl alcohol in the presence of dry gas to form: — Biomolecules Chemistry Question
Question
Glucose reacts with anhydrous methyl alcohol in the presence of dry $HCl$ gas to form:
Answer: D
💡 Solution & Explanation
Glucose acts as a cyclic hemiacetal. It reacts with $CH_3OH$ in the presence of dry $HCl$ selectively at the anomeric carbon (C1) to form an acetal linkage (glycosidic bond), yielding a mixture of $\alpha$ and $\beta$ methyl glucosides. The other hydroxyl groups are unaffected under these conditions.
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