The total number of amines among the following which can be synthesized by Gabriel synthesis is — Amines Chemistry Question

💡 Solution & Explanation

# Gabriel Synthesis Analysis **Step 1: Recall Gabriel synthesis requirements** Gabriel synthesis produces only **primary amines (RNH₂)** by reacting alkyl halides with potassium phthalimide, followed by hydrazine treatment. **Step 2: Identify what cannot be synthesized** - Secondary amines (R₂NH) — Cannot be made - Tertiary amines (R₃N) — Cannot be made - Aromatic amines (Ar-NH₂) — Cannot be made (aryl halides don't undergo nucleophilic substitution readily) **Step 3: Identify what can be synthesized** Only **aliphatic primary amines** with alkyl groups can be synthesized via Gabriel synthesis: - CH₃NH₂ (methylamine) ✓ - C₂H₅NH₂ (ethylamine) ✓ - (CH₃)₂CHNH₂ (isopropylamine) ✓ **Step 4: Count valid structures** From the given options, identify primary amines derived from alkyl halides: - Three structures meet Gabriel synthesis criteria **Step 5: Verify no exceptions** Confirm none are secondary, tertiary, or aromatic amines that would be incompatible with the synthesis. Therefore, the answer is 3.00.