The pKa of acetylsalicylic acid (aspirin) is 3.5. The pH of gastric juice in human stomach is about β Ionic Equilibrium Chemistry Question
Question
The pKa of acetylsalicylic acid (aspirin) is 3.5. The pH of gastric juice in human stomach is about 2 to 3 and the pH in the small intestine is about 8. Aspirin will be
Answer: D
π‘ Solution & Explanation
Aspirin is a weak acid. In the stomach (pH 2-3 < pKa 3.5), mostly unionized. In the small intestine (pH 8 >> pKa 3.5), mostly ionized.
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