In following reaction chain HO-C(=O)-CH2-CH(NH3+)-COOH (Aspartic acid) ⇌ HO-C(=O)-CH2-CH(NH3+)-COO- (Zwitterion) [pKa1 = 1.9] ⇌ -O-C(=O)-CH2-CH(NH3+)-COO- [pKa2 = 3.7] ⇌ -O-C(=O)-CH2-CH(NH2)-COO- [pKa

Question

In following reaction chain

HO-C(=O)-CH2-CH(NH3+)-COOH (Aspartic acid) ⇌ HO-C(=O)-CH2-CH(NH3+)-COO- (Zwitterion) [pKa1 = 1.9]
⇌ -O-C(=O)-CH2-CH(NH3+)-COO- [pKa2 = 3.7]
⇌ -O-C(=O)-CH2-CH(NH2)-COO- [pKa3 = 9.60]

The isoelectric point of aspartic acid is

Prashant Kotian · Accepted Answer

Correct answer: A. 1 2 pKa pKa pI 2   Isoelectric point (PI) 1 2 a a pK pK 2  

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